As outlined by a study by Unalp et al., Fournier's Gangrene Severity Index (FGSI) > 9, diabetes mellitus and sepsis on admission were located to be things for an D Candida parapsilosis, which may have contributed towards the development of unfavorable prognosis . Aggressive debridement from the wound PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/29069523 was H following CCI. The same dose was repeated every 24 h by followed by twice day-to-day dressings with NaCl 15 solution and betadine resolution. No skin graft was used. Our patient was also treated for diabetes mellitus and depression. On follow-up 2 months later, a significant improvement within the wound was noted. Nevertheless, the patient presentedJournal of Health-related Case Reports 2009, 3:http://jmedicalcasereports.com/jmedicalcasereports/article/view/We need to note that Fournier's gangrene may well represent the sole sign of underlying malignancy, as was reported inside a Romanian study exactly where such a case was the distinctive sign of a reduce rectal adenocarcinoma . Fournier's gangrene may possibly nonetheless have an idiopathic origin that commonly leads to a refractory situation [8,9]. It really should be described that our patient was a 65-year-old man with diabetes and anemia and with benign polyps in the sigmoid colon. Fajdic et al.On from normal is graded from 0 to 4. Parameters examined include temperature, heart rate, respiratory rate, serum sodium, potassium, creatinine PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25112874 and bicarbonate levels, hematocrit and leukocyte count. Regression evaluation among various studies has shown a strong correlation involving the FGSI score and also the death rate. In a recent study by Fajdic et al. such as seven male patients with imply age 61 years ranging from 57 as much as 66 years, it was shown that diabetes mellitus, urethrostenosis, hemorrhoids, anal fissure and abscesses may be strongly correlated with Fournier's gangrene . According to a study by Unalp et al., Fournier's Gangrene Severity Index (FGSI) > 9, diabetes mellitus and sepsis on admission had been found to be elements for an unfavorable prognosis . Chronic renal failure, hepatic failure, prosthetic penile implants, AIDS, malignancy and obesity had been also essential risk things. Fournier's gangrene has been described in immunosuppressed sufferers following liver, renal or perhaps cord blood stem cell transplantation [4,5].Web page two of(page quantity not for citation purposes)Figure 1. Fournier's gangrene. Swelling lesions on the scrotum and penis with edematous and irregular ulcer edges. lesion around the penis and scrotum. The edges from the ulcer had been edematous and irregular. The surrounding tissues were rather necrotic. A brown, seropurulent, exudative, and mousy odor was characteristic. Decolorization of the skin was also found and also the wound invasion was rather rapidly rising. Fournier's gangrene was diagnosed. Comorbidity integrated diabetes mellitus recognized for the final five years and important depression known for the last 25 years. Microbiological testing returned: Hct: 31.7 , Hb: 11.two g/dl, WBC: 26,three K/ml (neut/lymph: 92.four /4 ), PLT: 326 K/ml, urea: 106 mg/dl, creatinine: 1.7 mg/dl, Na: 139 mMol/L, K: 4.1 mMol/L, Leu: six g/dl, Alb: two.two g/dl. A computed tomography (CT) scan revealed that the liver and spleen had been enlarged and that the prostate gland showed benign hypertrophy.